Weight Loss

6 Vital Tips For Fasting – WOMEN Edition

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6 Vital Tips For Fasting – WOMEN Edition – Thomas DeLauer

Cruciferous vegetables contain goitrogens – a goitrogen, so named because an enlargement of the thyroid gland is known as a goiter, suppresses the thyroid gland by inhibiting the uptake of iodine

Iodine is one of the two building blocks of thyroid hormone, and if you are deficient in it, you can develop hypothyroidism (an underactive thyroid)

Cruciferous vegetables are rich in two different goitrogens: isothiocyanates and thiocyanates

have found that the consumption of cruciferous vegetables has little to no effect on the thyroid, unless a person is deficient in iodine

One study in humans, published in the journal Human Toxicology, found that the consumption of 150 g/day (5 oz/day) of cooked Brussels sprouts for four weeks had no adverse effects on thyroid function

https://www.ncbi.nlm.nih.gov/pubmed/2419242

Caffeine is known to inhibit cyclic nucleotide phosphodiesterases (PDEs), leading to an increase in cytosolic cAMP (activated by catecholamines) and stimulation of downstream cAMP-dependent mechanisms

Caffeine has been found to inhibit slow waves and associated myosalpinx contractions; this may be the result of elevated levels of cytosolic cAMP

Caffeine hyperpolarized membrane potential, abolished slow waves and inhibited myosalpinx contractions

Spontaneous electrical activity, termed slow waves, drives rhythmic, propulsive contractions in the smooth muscle of the oviduct (myosalpinx).

Myosalpinx contractions cause egg transport through the oviduct. Agents that disrupt slow wave pacemaker activity will therefore disrupt myosalpinx contractions and egg transport

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111677/

Study – Obesity Research

This study suggests that fasting could reduce women’s insulin sensitivity slightly more than men’s, causing their blood sugar to spike higher after a meal

Looked at the response of alternate day fasting in eight men and eight women

Glucose and insulin responses to a standard meal were tested in nonobese subjects at baseline and after 22 days of alternate day fasting (36 hour fast)

Glucose response to a meal was slightly impaired in women after 3 weeks of treatment, but insulin response was unchanged

However, men had no change in glucose response and a significant reduction in insulin response

In other words, women had slightly diminished insulin sensitivity also makes it harder to digest carbs and absorb nutrients, increasing the odds of gaining weight

https://www.ncbi.nlm.nih.gov/pubmed/15833943

Weight Training

Prevents catabolism

Meta Analysis – Nutrients

Looked to see if resistance training prevents muscle loss induced by caloric restriction

The review randomized clinical trials (RCT) comparing the effects of CR with (CRRT) or without RT on lean body mass (LBM), fat body mass (FBM), and total body mass (BM)

The six RCTs included in the review applied RT three times per week, for 12 to 24 weeks, and most CR interventions followed diets of 55% carbohydrate, 15% protein, and 30% fat

RT reduced 93.5% of CR-induced LBM loss (0.819 kg [0.364 to 1.273]), with similar reduction in FBM and BM, compared with CR

Concluded that CRRT is able to prevent almost 100% of CR-induced muscle loss, while resulting in FBM and BM reductions that do not significantly differ from CR.

https://www.ncbi.nlm.nih.gov/pubmed/29596307

The mineralocorticoids (primarily t) regulate the balance of minerals (sodium, potassium, and magnesium) in the cells

Stress triggers the release of aldosterone, which raises blood pressure by its action on cells to hold onto sodium and lose potassium

Long-term release of stress levels of mineralocorticoids can cause a potassium deficiency and a magnesium imbalance, as well as chronic water retention and high blood pressure

*Perimenopause, or menopause transition, begins several years before menopause. It’s the time when the ovaries gradually begin to make less estrogen*

https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/perimenopause

rbGH (recombinant bovine growth hormone), also known as rbST (recombinant bovine somatotropin), is a genetically engineered hormone injected into dairy cows to increase milk production.

rBST raises the concentration of insulin-like growth factor-1 (IGF-1) in treated cow milk

During development of the mammary system, IGF-1 increases cell proliferation and the formation of mammary ducts

Resources

1) https://www.ncbi.nlm.nih.gov/pubmed/2419242
2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111677/
3) http://www.agbioforum.org/v3n23/v3n23a15-brinckman.htm#R5
4) https://www.ncbi.nlm.nih.gov/pubmed/10435273
5) https://www.ncbi.nlm.nih.gov/pubmed/19034633

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