Weight Loss

Why I’ve Used a Standing Desk for 8 Years

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Why I’ve Used a Standing Desk for 8 Years – Thomas DeLauer

Hey, it’s no surprise that standing a little bit more is better for you than sitting down. All right? Now I’m never one to conform to just very basic broad health topics. I go deep. I go out there. I try to bake it down so that you actually know what’s truly happening in your body so today, I want to give you the knowledge that you can use to really understand why you’re gonna burn more fat and why you’re gonna ultimately look and feel better if you just stand up every now and then.

All right, so again, no blanket health topic here. We’re talking about some weird kinda science that’s gonna make you say wow when it comes down to standing up every now and then. All right, so the first thing we want to look at is yes, we do know that most people say you should be standing 80% of the time and sitting 20% of the time. I don’t know who came up with that number but it seems like it’s totally out of right field and it’s totally random. So I don’t necessarily think that’s the way, but what you do need to understand is the cellular systems and processes and what is metabolically within your body.

So the biggest issue that we’re facing, whenever it comes down to sitting for too long, is we are deactivating a very specific enzyme known as lipoprotein lipase, LPL. So what ends up happening is when we’re sitting down, we’re not triggering this enzyme to release fat from our adipose tissue. The way that fat burning works in sort of a nutshell is lipoprotein lipase triggers the release of fats from our storage form into our bloodstream. Once they’re in our bloodstream, then they get acted upon by another enzyme known as hormone-sensitive lipase. Then and only then does what is called lipolysis, fat burning, actually occur. So if we are lacking lipoprotein lipase, the enzyme that actually allows the fat to get back into the bloodstream, we’re never mobilizing fat to actually burn.

So sure, calories in, calories out. If you’re sitting down, you’re not burning many calories. Yeah, we know that, but you’re actually forgetting the biggest part. You’re not activating the enzyme that turns on fat burning.

So here’s where things get really, really cool. Did you know that within 90 seconds of standing up, you are activating metabolic pathways. Every single cell that is in your skeletal system, your muscular system, and of course all other kind of cellular function is activated. When you’re sitting down, it’s not activated. You’re just kind of operating at the bare minimum, but within 90 seconds of standing, your muscle cells activate, and these are the things that burn up triglycerides and mobilize them but also what regulates and activates the utilization of glucose and regulates your blood sugar.

So without this process occurring, you’re in this sort of dormant state, but what a lot of people don’t realize is that it happens in just 90 seconds. You stand up, within 90 seconds, you’re activating those enzymes and you’re activating those cells.


1) Thorp AA , et al. (n.d.). Breaking up workplace sitting time with intermittent standing bouts improves fatigue and musculoskeletal discomfort in overweight/obese office work… – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/25168375
2) Wilmot EG , et al. (n.d.). Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis. – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/22890825
3) Pronk NP , et al. (n.d.). Reducing occupational sitting time and improving worker health: the Take-a-Stand Project, 2011. – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/23057991
4) How Sitting Too Much Is Making Us Sick and Fat — And What to Do About It. (2013, May 18). Retrieved from https://www.huffingtonpost.com/chris-kresser/sitting-health_b_2897289.html
5) Buckley JP , et al. (n.d.). Standing-based office work shows encouraging signs of attenuating post-prandial glycaemic excursion. – PubMed – NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/24297826
6) Does Sitting Time Decrease Your Lifespan (Even If You Exercise)? (2016, June 13). Retrieved from https://thehealthsciencesacademy.org/health-tips/sitting-time/
7) Stand up straight, and you’ll feel better. (2014, May 2). Retrieved from https://www.psychologies.co.uk/self/life-lab-experiment-mind.html
8) Effect of frequent interruptions of prolonged sitting on self-perceived levels of energy, mood, food cravings and cognitive function. (n.d.). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094084/
9)Benefits of Increased Blood Circulation. (n.d.). Retrieved from http://www.mannaplus.co.za/benefits-of-increased-blood-circulation-2/

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